7, 8 In corneas with undiagnosed disease states, refractive surgery can be followed by a progressive and sometimes unrecoverable corneal shape change. In such procedures, the biomechanical properties of the cornea are altered and mediate secondary mechanical shape changes of the corneal surface. Refractive surgery procedures such as laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) are performed to reduce spectacle or contact lens dependence by altering the corneal shape and refractive power. 1 Although stiffening by corneal collagen crosslinking (CXL) is a promising emerging treatment for ectatic disease, 2 the biomechanical features of ectatic disease and the impact of CXL on target tissues have not been fully characterized, in part because of a paucity of clinical tools for biomechanical characterization. Diseases such as keratoconus, pellucid marginal degeneration, and keratoglobus distort this shape and are hypothesized to involve a primary disorder of biomechanical strength. Get helpįor assistance with any technology product or service at Case Western Reserve University, contact the Tech Service Desk at or (4357) or visit shape of the cornea and its optical properties are greatly influenced by the biomechanical properties of its constituent tissue.
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